We estimate the contribution of parental substance abuse on offspring psychiatric morbidity in late adolescence and early adulthood, with emphasis on the timing and persistency of exposure. We used a nationally representative 20% sample of Finnish families with children born in 1986-1996 (n=136,604) followed up in 1986–2011. We identified parental substance abuse and offspring psychiatric morbidity from hospital discharge records, death records and medication registers. Parental substance abuse at ages 0-14 was associated with about 2-fold increase in offspring psychiatric morbidity. Adjustment for childhood parental education, income, social class and family type reduced these effects by about 50%, with some further attenuation after adjustment for time-varying offspring characteristics. In fixed effects models those exposed at 0-4 or 5-9 years had 20-30% excess morbidity. Furthermore, early exposure at ages 0-4 combined with repeated exposure in later childhood had about 80-90% higher psychiatric morbidity as compared to never exposed siblings.
Presented in Session 248. Determinants of Adolescent Health